Zhang J, Qin Y, Fu A, Tang J, Chen G, Cai D, Han J.  
Institute of Cardiovascular Research,
Beijing Medical University,
100083, Beijing,
China  

Gene transfer is one of the key techniques in gene therapy application. Unfortunately, it seems that by now, there still exists no approach with simplicity, easiness, efficiency and safety. A novel method for gene delivery, electreacupuncture needle-mediated gene transfer which combined the Chinese traditional acupuncture with modem gene introduction, was developed. With acupuncture needle carrying exogenous gene into muscle after direct electronic stimuli, efficient gene delivery was achieved.