Musial F, Tao I, Dobos G.   Innere Medizin V, Naturheilkunde und Integrative Medizin, Kliniken Essen-Mitte, Knappschafts-Krankenhaus, Universität Duisburg-Essen, Stiftungsprofessur für Naturheilkunde, Essen, Deutschland. f.musial@kliniken-essen-mitte.de  

The German acupuncture trials ART and GERAC have shown that acupuncture and sham or minimal acupuncture were equally effective in the reduction of chronic pain symptoms. These results have prompted an ongoing discussion as to whether acupuncture exerts its effects through a placebo response. Increasing knowledge about the neurobiology of pain and its intrinsic control suggests a combination of acupuncture-specific neurophysiologic effects combined with effects that match those of expectation-induced placebo analgesia.